Advance your cell model with our scalable cell culture platform with physiological flow

Enabling you to create more human-relevant, predictive and reproducible assays, without changing your workflow.

Book a demoExplore the platform

MACplate

Standard well-plate, standard operation, standard read-out.

24 well-plate. A 96 well-plate is in the pipeline.

Trusted by

(Pilot) customers

  • Erasmus MC
  • University of Galway

Partners / Backed by

  • Eindhoven University of Technology
  • Coevering
  • Axxicon
  • Demcon
  • Brabantse Ontwikkelings Maatschappij
  • Brabant Startup Fonds
  • Rabobank
  • NWO
  • Co-funded by the European Union
  • Health~Holland
  • MIT Zuid
  • Metropoolregio Eindhoven
  • 4TU Startups
  • DayOne
  • The Gate — Brainport Eindhoven
  • TTT MedTech
  • Venture Challenge
  • Eindhoven University of Technology
  • Coevering
  • Axxicon
  • Demcon
  • Brabantse Ontwikkelings Maatschappij
  • Brabant Startup Fonds
  • Rabobank
  • NWO
  • Co-funded by the European Union
  • Health~Holland
  • MIT Zuid
  • Metropoolregio Eindhoven
  • 4TU Startups
  • DayOne
  • The Gate — Brainport Eindhoven
  • TTT MedTech
  • Venture Challenge

Today’s lab models do not represent how the body really works. We bring biology closer to reality.

Current static models show limited predictivity of in vivo conditions, while dynamic models are difficult to use. We add human-relevant dynamic conditions without sacrificing today’s lab workflows.

TodayStandard well-plate
Standard 24 well-plate: static culture in every well
With MACplateARTIC's MAC-plate
ARTIC MACplate: magnetic artificial cilia channels added to every well of a 24 well-plate

Human-relevant assays

Create dynamic cell culture conditions that better reflect the in vivo microenvironment.

Fits your workflow

Compatible with standard well plates, Transwells and laboratory automation.

Built for scale

Increase throughput without increasing experimental complexity.

High sensitivity and reproducibility

Enhance compound exposure and improve detection of subtle assay responses.

Accelerated tissue maturation

Dynamic culture supports faster development of functional cell models.

Applications

Gut permeability

Gut permeability

Improve detection of challenging low-permeability compounds.

Immuno-oncology

Immuno-oncology

Dynamic tumor-immune cell infiltration and interaction.

Further applications

Further applications

Dynamic tissue models across a wide range of biomedical applications.

  • Enhancing tissue maturation
  • Inflammation
  • Vascularized tissue
From nature to assay

The technology

In nature, hair-like cilia create flow in and on organisms — including your own airways. We mirror that principle with Magnetic Artificial Cilia (MAC): microscopic actuators integrated into a standard well plate. Powered by MACnet, they generate controlled fluid flow inside MACplate.

01Nature-inspired
02Magnetic actuation
03Controlled flow
01 — The ciliaMagnetic Artificial Cilia beat under a controlled magnetic field.
Cross-section schematic: cilia in the channel drive flow underneath the cell layer in a well insert
02 — In the wellThat flow runs through the channel underneath the insert, past the cell layer.
How it works
Step 01
123456
ABCD

MACplate

Standard well-plate, standard operation, standard read-out.

24 well-plate. A 96 well-plate is in the pipeline.

1Step 01

Seed your cells

Seed your cells in standard Transwell supports.

Step 1: Seed your cells
2Step 02

Place MACplate on MACnet

Place MACplate on top of MACnet in the incubator.

Step 2: Place MACplate on MACnet
3Step 03

Press run

Press run. Flow starts!

Step 3: Press run

Who it's for

CROs

Expand your assay portfolio with human-relevant dynamic models.

  • Differentiate your service offering
  • Increase laboratory efficiency
  • Remain compatible with existing workflows

Pharma

Improve confidence in preclinical decision-making.

  • Human-relevant dynamic assays
  • Better compound selection before animal studies
  • Generate more informative in vitro data

Cell model providers

Enhance the performance of your cell models.

  • Support tissue maturation
  • Shorten differentiation timelines
  • Reduce hands-on laboratory time

Academia

Bring dynamic culture to your research without changing your workflow.

  • More physiologically relevant models
  • Compatible with standard laboratory equipment
  • Maintain throughput and ease of use

Welcome to FAQ!

Everything You May Want to Know About Our Solution

The cilia are cylindrical in size, with a diameter of 50 µm and a height of 350 µm.

Let's talk

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